| SDY519: Monozygotic and Dizygotic Twin Pair T-Cell Responses to Influenza Vaccination 2011 | 
    
      | Status: | New | 
    
      | Description: | Evaluate the variation in immune response between individuals and assess whether it changes as a function of age and similarity in genetic and environmental background (by comparing differences between monozygotic and dizygotic twin pairs of different ages). | 
    
      | Program/Contract: | 
        
          
            | Program | Contract |  
            | Human Immunology Project Consortium 1 (HIPC1) | Vaccination and infection: indicators of immunological health and responsiveness |  | 
    
      | DOI: | 10.21430/M3TI6PGH9Q | 
    
      | Subjects: | 63 | 
    
      | Study PI, contact: | 
        
          
            | Name | Organization | Site |  
            | Mark Davis | Stanford University | Stanford-LPCH Vaccine Program |  | 
    
      | Publications: | 
        
        
        
          
            | Variation in the human immune system is largely driven by non-heritable influences.. Cell. Jan 2015. doi: 10.1016/j.cell.2014.12.020.
             [Pubmed: 25594173] |  | 
    
      | Resources: |  | 
    
      | Assays: | 
        
          
            | Assay Type | Number of Exp. Samples |  
            | CyTOF | 127 |  
            | Flow Cytometry | 432 |  
            | Hemagglutination Inhibition | 118 |  
            | Luminex xMAP | 396 |  | 
    
      | Clinical Assessments: | None |